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Partially Immitation Uno

Maybe this why they call it pim1? See here, its a kinase without a key hydrogen bond donor. Highlit yellow is the interesting PRO123. ATP and inhibitors generally bind to the peptide NH that is...

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PDB Update

>>  update: Amanda‘s already on the scene… and fascinated. 2OI4′s ‘nother one of them CP-Ruthenium/Stuarosporine things bound to PIM1 related: 2BZH, 2BZI, 2BZJ

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Chiron’s got Pim

WO/2008/106692 is Novartis’ Emeryville’s Pim1,2,3 < 1uM offering:

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WO/2008/124323

Array’s got Pim: Posted in Array, pim1

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SGI-1776

Supergen’s Pim kinase inhibitor via WO/2008/58126: Structure described at AACR. (keep’m coming please I know there’s more!) Posted in pim1, Supergen

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